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Browsing by Author "Das, Sajal"

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    Investigations on synthetic organic transformations : application to C-C and C-N bond forming processes
    (University of North Bengal, 2007) Das, Sajal; Basu, B
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    Metal free C- H Functionalization: a unique tool for library synthesis of functionalized 4- pyrimidiones
    (University of North Bengal, 2023) Roy, Sanjay; Das, Sajal
    The Present Thesis entitled as “Metal free C- H Functionalization: a unique tool for library synthesis of functionalized 4-pyrimidiones” has made some efforts to synthesize the diverse 4 pyrimidones with varied functional groups via different approaches and their applications in medicinal and pharmacological domains. Based on different direction and contents of the work; the thesis has been divided into four chapters. Chapter I: describes an introduction to present work, the “A brief review on C-H functionalization/activation and a literature study regarding the synthesis of 4Hpyrido[ 1,2-a]pyrimidin-4-one derivatives” Summarizes a brief review on pyrimidines and it was further subdivided into following points: 1) Origin, background theory, importance and current status of C-H Functionalization. 2) Use of C-H functionalization techniques in selective functionalization of heterocycles. 3) Importance of 4-pyrimidiones and current literature status 4) Different approaches of its synthesis and further derivatization Chapter II: describes “Microwave-assisted straight forward synthesis of 2-substituted alicyclic fused pyrimidone” We have divulged here a metal free- and MW assisted route to tetrahydro-4H-pyrido[1,2- a]pyrimidin-4-one and dihydropyrrolo[1,2-a]pyrimidin-4(6H)-one has been demonstrated by the reaction of aminoacrylates with lactams in presence of phosphorous pentachloride. This transformation comprises of the sequential formation of three new bonds to produce pyrimidone derivatives under mild reaction conditions and this strategy is well compatible for both electron deficient and electron rich amino-acrylates. This method is amenable for gram scale reaction.
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    Novel pd-catalyzed carbon-carbon and carbon-heteroatom cross coupling reactions towards the synthesis of diverse functional molecules
    (University of North Bengal, 2021) Mondal, Biswajit; Das, Sajal; Kundu, Mrinalkanti
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    Synthesis of palladium - N - heterocyclic carbene complexes and their application in organic transformations
    (University of North Bengal, 2014) Gupta, Sumanta; Das, Sajal
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